MBS670185 | Mouse Anti-Human IL-21-UNLB

Mouse Anti-Human IL-21-UNLB | MBS670185 | MyBiosource

Product Short Name: [IL-21]

Product Name Synonyme: [Mouse anti-Human Interleukin-21 (IL-21)]

Other Names: [interleukin-21 isoform 2; Interleukin-21; interleukin-21; interleukin-21 isoform; interleukin 21; Za11]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [IL21; IL21; Za11; IL-21; IL-21]

Clonality: Monoclonal

Isotype: IgG2a

Clone: [SB134f]

Host: Mouse

Reactivity: Human

Specificity: Reacts with human IL-21
Interleukin-21 (IL-21) is a four helical bundle type I cytokine1. The mature form of human IL-21 is a 131 amino acid protein.4 IL-21 is expressed primarily by NKT and CD4+ T cells, particularly the inflammatory Th17 subset and has pleiotropic effects on both innate and adaptive immune responses. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of Tcells and augmentation of antitumor activity of CD8+ T cells.2, 3 Recent studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases. Clone SB134f can be used as a detection antibody for sandwich ELISA.5

Purity: N/A

Form: Purified (UNLB) Antibody

Concentration: N/A

Storage Stability: The purified (UNLB) antibody is supplied as 0.5mg purified immunoglobulin in 1.0mL of 100mM borate buffered saline, pH 8.2; store at 2-8 degree C.

Tested Application: ELISA