MBS670144 | Mouse Anti-Human SMAC/DIABLO-UNLB

Mouse Anti-Human SMAC/DIABLO-UNLB | MBS670144 | MyBiosource

Product Short Name: [SMAC/DIABLO]

Product Name Synonyme: [Mouse Anti-Human SMAC/DIABLO - Purified, Unlabeled Antibody; Mouse Anti-Human SMAC/DIABLO]

Other Names: [Smac/DIABLO-S protein; Diablo homolog (Drosophila); diablo homolog, mitochondrial; 0610041G12Rik; OTTHUMP00000211306; OTTHUMP00000211307; OTTHUMP00000211309; OTTHUMP00000239748; OTTHUMP00000239749; mitochondrial Smac protein; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; diablo, IAP-binding mitochondrial protein]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [DIABLO; DIABLO; SMAC; SMAC3; DIABLO-S; FLJ10537; FLJ25049]

Clonality: Monoclonal

Isotype: Mouse IgG2b

Clone: [2D12]

Host: Mouse

Reactivity: Human

Specificity: Human SMAC/DIABLO
SMAC/DIABLO (second mitochondria-derived activator of caspase/direct IAP-binding protein with low PI) is a mitochondrial protein that functions as a regulatory component during apoptosis. It is encoded by a nuclear gene and is subsequently imported into the mitochondria where the N-terminus is removed generating the mature form of the molecule. SMAC/DIABLO has been shown to neutralize the antiapoptotic effect of the inhibitor of apoptosis protein (IAP) family, a major group of apoptosis regulators that have been shown to directly block caspase activity thereby blocking apoptosis. 1-6

Purity: N/A

Form: Purified (UNLB) Antibody

Concentration: N/A

Storage Stability: The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C.
Reagents are stable for the period shown on the label if stored as directed.

Tested Application: ELISA; Western Blot