MBS670143 | Mouse Anti-Human TLR6-UNLB

Mouse Anti-Human TLR6-UNLB | MBS670143 | MyBiosource

Product Short Name: [Toll-like Receptor 6 (TLR6)]

Product Name Synonyme: [Mouse Anti-Human TLR6 - Purified, Unlabeled Antibody; Mouse Anti-Human Toll-like Receptor 6 (TLR6)]

Other Names: [toll-like receptor 6; Toll-like receptor 6; toll-like receptor 6; OTTHUMP00000218187; toll-like receptor 6]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [TLR6; CD286]

Clonality: Monoclonal

Isotype: Mouse IgG2a

Clone: [3B6]

Host: Mouse

Reactivity: Human

Specificity: Human Toll-like Receptor 6 (TLR6)
The Toll-like receptor (TLR) family is comprised of Type I transmembrane proteins characterized by an extracellular leucine-rich domain and a cytoplasmic tail that contains a conserved region call the Toll/IL-1 (TIR) domain. First discovered in Drosophila, TLRs recognize specific molecular patterns that are present in microbial components and respond to these components in order eliminate or limit invading microbes. To date, ten mammalian homologs of TLRs have been described. TLRs signal through adaptor molecules such as MyD88 leading to NF- kappa B activation, c-Jun N-terminal kinase activation (JNK), cytokine secretion and the inflammatory response. The amino acid sequence of human TLR6 is most similar to hTLR1 with 69% identity. TLR6 recognizes mycoplasmal macrophage-activating lipopeptide- 2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B. burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.1-6

Purity: N/A

Form: Purified (UNLB) Antibody

Concentration: N/A

Storage Stability: The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C.
Reagents are stable for the period shown on the label if stored as directed.

Tested Application: ELISA; Flow Cytometry