MBS670122 | Mouse Anti-Human GSK-3b-SEPH

Mouse Anti-Human GSK-3b-SEPH | MBS670122 | MyBiosource

Product Short Name: [GSK-3 beta ]

Product Name Synonyme: [Mouse Anti-Human GSK-3b - Sepharose-Labeled; Mouse Anti-Human GSK-3 beta ]

Other Names: [glycogen synthase kinase-3 beta isoform 2; Glycogen synthase kinase-3 beta; glycogen synthase kinase-3 beta; GSK-3 beta; GSK3beta isoform; OTTHUMP00000165239; OTTHUMP00000165240; glycogen synthase kinase 3 beta]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [GSK3B; GSK3B; GSK3B]

Clonality: Monoclonal

Isotype: Mouse IgG2b

Clone: [5D6]

Host: Mouse

Reactivity: Human

Specificity: Human GSK-3 beta
Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3 alpha and GSK-3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.

Purity: N/A

Form: Sepharose 4B (SEPH) Conjugate

Concentration: N/A

Storage Stability: The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C.
The Sepharose 4B (SEPH) conjugate is supplied as 50 tests in 2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C. Shake well before use.
Reagents are stable for the period shown on the label if stored as directed.

Tested Application: ELISA; Immunoprecipitation; Western Blot