MBS670120 | Mouse Anti-GSK-3a-SEPH

Mouse Anti-GSK-3a-SEPH | MBS670120 | MyBiosource

Product Short Name: [GSK-3 alpha ]

Product Name Synonyme: [Mouse Anti-GSK-3a - Sepharose-Labeled; Mouse Anti-GSK-3 alpha ]

Other Names: [glycogen synthase kinase-3 alpha; Glycogen synthase kinase-3 alpha; glycogen synthase kinase-3 alpha; GSK-3 alpha; OTTHUMP00000198366; OTTHUMP00000198367; OTTHUMP00000198368; glycogen synthase kinase 3 alpha]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [GSK3A; GSK3A; DKFZp686D0638]

Clonality: Monoclonal

Isotype: Mouse IgG2a

Clone: [SBGSK3 alpha 4]

Host: Mouse

Reactivity: N/A

Specificity: Human, mouse and rat GSK-3 alpha
Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3 alpha and GSK-3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.

Purity: N/A

Form: Sepharose 4B (SEPH) Conjugate

Concentration: N/A

Storage Stability: The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C.
The Sepharose 4B (SEPH) conjugate is supplied as 50 tests in 2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C. Shake well before use.
Protect conjugated forms from light. Reagents are stable for the period shown on the label if stored as directed.

Tested Application: Immunoprecipitation; Western Blot