MBS570197 | Mouse anti Human vitronectin receptor CD51

Mouse anti Human vitronectin receptor CD51 | MBS570197 | MyBiosource

Product Short Name: [vitronectin receptor CD51]

Product Name Synonyme: N/A

Other Names: N/A

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: N/A

Clonality: Monoclonal

Isotype: IgG1

Clone: [NKI-M7 (former AMF7)]

Host: Mouse (Balb/c)

Reactivity: Human

Specificity: T-lymphocyte clones NKI-M7 detect a melanoma-associated proteoglycan (MW greater than 450-250 kDa) and a molecular complex, which under reducing conditions consists of 4 compounds of 120, 95, 29 and 25 kDa respectively. NKI-M7 reacts with cultured melanomas melanomas in frozen sections. The antigen detected by NKI-M7 is strongly associated with the adhesion and cytoplasmic spreading of melanoma cells to plastic surfaces and monolayers of vascular endothelial cells. NKI-M7 blocks fibronectin-induced chemotaxic motility and chemokinesis of melanoma cells. In addition to their membrane localization, the antigens detected by NKI-M7are abundant in extracellular adhesion plaques deposited by cultured melanoma cells. NKI-M7 stains primary tumors heterogeneously, whereas metastases are homogeneously stained.

Purity: N/A

Form: Each vial contains 1ml of culture supernatant of monoclonal antibody containing 0.09% sodium azide.

Concentration: N/A

Storage Stability: Store at 4 degree C, or in small aliquots at -20 degree C.

Tested Application: ELISA (EIA), Flow Cytometry (FC), Immunohistochemistry (IHC) (frozen), Immunoprecipitation (IP)