MBS439953 | Protocadherin FAT2 (FAT Atypical Cadherin 2)

Protocadherin FAT2 (FAT Atypical Cadherin 2) | MBS439953 | Mybiosource

Product Short Name: [Protocadherin FAT2]

Product Name Synonyme: [FAT tumor suppressor homolog 2 (HFAT2); cadherin family member 8 (CDHF8); cadherin-related family member 9 (CDHR9); multiple EGF-like domains protein 1; multiple epidermal growth factor-like domains 1 (MEGF1); multiple epidermal growth factor-like domains protein 1; protocadherin FAT2.]

Other Names: [protocadherin Fat 2; Protocadherin Fat 2; protocadherin Fat 2; FAT atypical cadherin 2; Cadherin family member 8; Multiple epidermal growth factor-like domains protein 1; Multiple EGF-like domains protein 1]

Product Gene Name: [FAT2]

Product Gene Name Synonyme: N/A

Other Gene Names: [FAT2; FAT2; CDHF8; CDHR9; HFAT2; MEGF1; SCA45; CDHF8; KIAA0811; MEGF1; hFat2; Multiple EGF-like domains protein 1]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [8C5]

Host: Mouse

Reactivity: Human. Others not known.

Specificity: Recognizes a protein of 480kDa, which is identified as FAT2. The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin