MBS439724 | CD22 / BL-CAM Mouse Monoclonal Antibody

CD22 / BL-CAM Mouse Monoclonal Antibody | MBS439724 | MyBiosource

Product Short Name: [CD22 / BL-CAM ]

Product Name Synonyme: [B-lymphocyte cell adhesion molecule (BL-CAM); B-cell receptor CD22; CD22; Lectin 2; Lyb8; Sialic acid-binding Ig-like lectin 2 (Siglec-2); SIGLEC2; T-cell surface antigen Leu-14 ]

Other Names: [B-cell receptor CD22 isoform 2; B-cell receptor CD22; B-cell receptor CD22; CD22 molecule; B-lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14; CD_antigen: CD22]

Product Gene Name: [CD22]

Product Gene Name Synonyme: N/A

Other Gene Names: [CD22; CD22; SIGLEC2; SIGLEC-2; SIGLEC2; BL-CAM; Siglec-2]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [FR10B4 ]

Host: Mouse

Reactivity: Human.
Others not tested

Specificity: Recognizes a protein of 130-140kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF)