MBS439570 | CD55 / Decay Accelerating Factor (DAF) Mouse Monoclonal Antibody

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MBS439570
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Description

CD55 / Decay Accelerating Factor (DAF) Mouse Monoclonal Antibody | MBS439570 | MyBiosource

Product Short Name: [CD55 / Decay Accelerating Factor (DAF) ]

Product Name Synonyme: [CD55; CD55 Cromer blood group system; Complement decay-accelerating factor; CROM; DAF; Daf-GPI; Decay Accelerating Factor for Complement; Decay accelerating factor GPI-form; Decay accelerating factor soluble-form; GPI-DAF ]

Other Names: [complement decay-accelerating factor isoform 1 preproprotein; Complement decay-accelerating factor; complement decay-accelerating factor; CD55 molecule (Cromer blood group); CD_antigen: CD55]

Product Gene Name: [CD55]

Product Gene Name Synonyme: N/A

Other Gene Names: [CD55; CD55; CR; TC; DAF; CROM; CR; DAF]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [143-30 ]

Host: Mouse

Reactivity: Human

Specificity: Recognizes a single chain glycoprotein of 70kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin

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