MBS439370 | CD46 (Membrane Cofactor Protein) Mouse Monoclonal Antibody

CD46 (Membrane Cofactor Protein) Mouse Monoclonal Antibody | MBS439370 | MyBiosource

Product Short Name: [CD46]

Product Name Synonyme: [AHUS2; Complement membrane cofactor protein; MCP; Measles virus receptor; Membrane cofactor protein; MIC10; TLX; Trophoblast leucocyte common antigen; Trophoblast lymphocyte cross reactive antigen ]

Other Names: [membrane cofactor protein isoform 1; Membrane cofactor protein; membrane cofactor protein; CD46 molecule; TLX; Trophoblast leukocyte common antigen; CD_antigen: CD46]

Product Gene Name: [CD46]

Product Gene Name Synonyme: N/A

Other Gene Names: [CD46; CD46; MCP; TLX; AHUS2; MIC10; TRA2.10; MCP; MIC10]

Clonality: Monoclonal

Isotype: IgG2a, kappa

Clone: [197-2B1 ]

Host: Mouse

Reactivity: Human.
Others not tested

Specificity: Recognizes a protein of 52kDa-58kDa, identified as CD46 (also known as membrane cofactor protein, MCP). CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria. This MAb can be applied to test complement activation in pseudo-allergic reactions to acetylsalicylic acid and to test for measles virus infection of cells.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF)