MBS438925 | CD43 (T-Cell Marker) Mouse Monoclonal Antibody

CD43 (T-Cell Marker) Mouse Monoclonal Antibody | MBS438925 | MyBiosource

Product Short Name: [CD43]

Product Name Synonyme: [Galactoglycoprotein, GALGP, GPL115, Leukocyte sialoglycoprotein, Leukosialin, LSN, Sialophorin, SPN ]

Other Names: [leukosialin; Leukosialin; leukosialin; sialophorin; Galactoglycoprotein; GALGP; Leukocyte sialoglycoprotein; Sialophorin; CD_antigen: CD43]

Product Gene Name: [SPN]

Product Gene Name Synonyme: N/A

Other Gene Names: [SPN; SPN; LSN; CD43; GALGP; GPL115; CD43; GALGP]

Clonality: Monoclonal

Isotype: IgM, kappa

Clone: [Bra7G ]

Host: Mouse

Reactivity: Human

Specificity: It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop V). Epitope of MAb Bra7G is clearly different from that of MAb DF-T1, called b as opposed to a for DF-T1. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by PEG precipitation. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin