MBS438849 | N-Cadherin/Cadherin-2/CD325 (NCAD)

N-Cadherin/Cadherin-2/CD325 (NCAD) | MBS438849 | Mybiosource

Product Short Name: [N-Cadherin/Cadherin-2/CD325 (NCAD)]

Product Name Synonyme: [Cadherin-2 N cadherin neuronal; Cadherin-2 type 1; Cadherin-2; Calcium dependent adhesion protein neuronal; CD325; CDH2; CDHN; CDw325; N-Cadherin; NCAD]

Other Names: [cadherin-2 isoform 2; Cadherin-2; cadherin-2; cadherin 2; CDw325; Neural cadherin; N-cadherin; CD_antigen: CD325]

Product Gene Name: [NCAD]

Product Gene Name Synonyme: [CDH2; CD325]

Other Gene Names: [CDH2; CDH2; CDHN; NCAD; CD325; CDw325; CDHN; NCAD; N-cadherin]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [13A9]

Host: Mouse

Reactivity: Human, Mouse. Others not known.

Specificity: Recognizes a protein of ~140kDa, identified as N-Cadherin (NCAD), also known as CD325. NCAD is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells. Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)