MBS438737 | Proximal Nephrogenic Antigen (Renal Cell Marker) Mouse Monoclonal Antibody

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MBS438737
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Description

Proximal Nephrogenic Antigen (Renal Cell Marker) Mouse Monoclonal Antibody | MBS438737 | MyBiosource

Product Short Name: [Proximal Nephrogenic Antigen]

Product Name Synonyme: [CA-IX, CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, Carbonic anhydrase IX, Carbonic dehydratase, G250, Membrane antigen MN, P54/58N, pMW1, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250 ]

Other Names: [carbonic anhydrase 9; Carbonic anhydrase 9; carbonic anhydrase 9; carbonic anhydrase 9; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1]

Product Gene Name: [CA9]

Product Gene Name Synonyme: N/A

Other Gene Names: [CA9; CA9; MN; CAIX; G250; MN; CA-IX; CAIX; RCC-associated antigen G250]

Clonality: Monoclonal

Isotype: IgG2b, kappa

Clone: [PN-15 ]

Host: Mouse

Reactivity: Human, Horse

Specificity: Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin

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