MBS438397 | VEGF-R2

VEGF-R2 | MBS438397 | MyBiosource

Product Short Name: [VEGF-R2]

Product Name Synonyme: [CD309; Fetal liver kinase 1 (FLK-1); KDR; Kinase insert domain receptor (a type III receptor tyrosine kinase); KRD1; Ly73; Protein tyrosine kinase receptor FLK1; Protein-tyrosine kinase receptor flk-1; Vascular endothelial growth factor receptor 2]

Other Names: [vascular endothelial growth factor receptor 2; Vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor 2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD_antigen: CD309]

Product Gene Name: [KDR]

Product Gene Name Synonyme: N/A

Other Gene Names: [KDR; KDR; FLK1; CD309; VEGFR; VEGFR2; FLK1; VEGFR2; VEGFR-2; FLK-1; KDR]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [KDR721]

Host: Mouse

Reactivity: Human.

Specificity: CD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

Purity: N/A

Form: N/A

Concentration: N/A

Storage Stability: Store at 2 to 8 degree C. Antibody is stable for 24 months.

Tested Application: ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Functional Studies, Immunoprecipitation (IP), Immunohistology (IH)