MBS4381658 | Coagulation Factor VII/F7

Coagulation Factor VII/F7 | MBS4381658 | Mybiosource

Product Short Name: [VII/F7]

Product Name Synonyme: [Eptacog alfa; Factor VII heavy chain; Factor VII light chain; FVII coagulation protein; Proconvertin; Serum prothrombin conversion accelerator (SPCA)]

Other Names: [coagulation factor VII isoform a preproprotein; Coagulation factor VII; coagulation factor VII; coagulation factor VII; Proconvertin; Serum prothrombin conversion accelerator]

Product Gene Name: [F7]

Product Gene Name Synonyme: N/A

Other Gene Names: [F7; F7; SPCA; SPCA]

Clonality: Monoclonal

Isotype: IgG2a, kappa

Clone: [F7/3511]

Host: Mouse

Reactivity: Human

Specificity: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor VII (serum prothrombin conversion accelerator, proconvertin, F7, Factor VII) is a 406 amino acid, vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. Factor IX A, Factor X A, Factor XII A or Thrombin-mediated proteolytic cleavage of Factor VII at Arg 152-Ile 153 generates Factor VII A, an active serine protease composed of a catalytic heavy chain disulfide linked to a light chain, containing two EGF-like domains. Mutations at the F7 locus that lead to Factor VII deficiencies are generally asymptomatic or phenotypically uncharacterized, with hemorrhagic diathesis occurring at extremely low levels.

Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: ELISA (EIA), Immunohistochemistry (IHC) Paraffin