MBS4381651 | LILRB1/ILT-2/CD85j

LILRB1/ILT-2/CD85j | MBS4381651 | Mybiosource

Product Short Name: [LILRB1/ILT-2/CD85j]

Product Name Synonyme: [CD85 antigen; CD85j antigen; Ig like transcript 2; immunoglobulin like transcript 2 (ILT2); leukocyte Ig like receptor 1; Leukocyte immunoglobulin like receptor 1; leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform; LILRB1; LIR1; Monocyte/macrophage immunoglobulin like receptor 7 (MIR7); PIRB]

Other Names: [leukocyte immunoglobulin-like receptor subfamily B member 1 isoform 4; Leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin like receptor B1; CD85 antigen-like family member J; Immunoglobulin-like transcript 2; ILT-2; Monocyte/macrophage immunoglobulin-like receptor 7]

Product Gene Name: [LILRB1]

Product Gene Name Synonyme: N/A

Other Gene Names: [LILRB1; LILRB1; ILT2; LIR1; MIR7; PIRB; CD85J; ILT-2; LIR-1; MIR-7; PIR-B; ILT2; LIR1; MIR7; LIR-1; Leukocyte immunoglobulin-like receptor 1; ILT-2; MIR-7]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [VMP55]

Host: Mouse

Reactivity: Human, Mouse, Rat

Specificity: Leukocyte immunoglobulin-like receptors (LIRs) are members of the immunoglobulin superfamily of glycoproteins and are predominantly expressed by monocytes, B cells, dendritic cells, natural killer (NK) cells, peripheral blood leukocytes and tissues such as placenta, lung and liver. Immunoglobulin-like transcript 2 (ILT-2), also known as CD85 or MIR7, is a 650 amino acid glycoprotein that contains a 23 amino acid signal peptide, 4 extracellular C2-type IGSF domains and 4 intracellular ITIM motifs. ILT-2 can bind major histocompatability (MHC) class I molecules and inhibit cell termination by natural killer (NK) and T cells, and inhibit Ca2+ mobilization in myeloid cells triggered through the B cell antigen receptor and histocompatibility leukocyte antigens (HLA)-DR. ILT-2 contains four putative cytoplasmic tyrosine-based inhibitory motifs and upon tyrosine phosphorylation, associates with the tyrosine phosphatase SHP-1.

Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunoprecipitation (IP), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)