MBS4381607 | SLAMF7/CS1/CD319

SLAMF7/CS1/CD319 | MBS4381607 | Mybiosource

Product Short Name: [SLAMF7/CS1/CD319]

Product Name Synonyme: [19A; 19A24 protein; CD2 like receptor activating cytotoxic cells; CD2 subset 1; CRACC; CS1; Membrane protein FOAP 12; Novel LY9 (lymphocyte antigen 9) like protein; Protein 19A; SLAM family member 7]

Other Names: [SLAM family member 7 isoform b; SLAM family member 7; SLAM family member 7; SLAM family member 7; CD2 subset 1; CD2-like receptor-activating cytotoxic cells; CRACC; Membrane protein FOAP-12; Novel Ly9; Protein 19A; CD_antigen: CD319]

Product Gene Name: [SLAMF7]

Product Gene Name Synonyme: N/A

Other Gene Names: [SLAMF7; SLAMF7; 19A; CS1; CD319; CRACC; CS1; CRACC]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [SLAMF7/3649]

Host: Mouse

Reactivity: Human

Specificity: CS1, also known as novel Ly9, SLAMF7, 19A24 or CRACC, is a homophilic cell surface receptor. It is a member of the SLAM (signaling lymphocytic activation molecule) family of receptors expressed on natural killer (NK) cells, T cells and stimulated B cells. CS1 contains immunoreceptor tyrosine-based switch motifs in its cytoplasmic domain but, unlike other SLAM receptors, it does not recruit SAP (SLAM-associated protein). In humans, CS1 activates NK cells through an EAT-2-mediated pathway that is SAP-independent. CS1 recruits and associates with EAT-2, a protein closely related to SAP. EAT-2 induces phosphorylation of CS1 which then, upon ligand binding, activates downstream cytotoxicity effectors PLC and PI 3K. In mice, the EAT-2 association with CS1 has an inhibitory effect on the activation of NK cells.

Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistochemistry (IHC) Paraffin