MBS4381532 | CD40, Mouse

CD40, Mouse | MBS4381532 | Mybiosource

Product Short Name: [CD40]

Product Name Synonyme: [B cell surface antigen CD40; CD40 type II isoform; p50; Bp50; CD40L receptor; CDW40; TRAP; IMD3; IGM; Tnfrsf5; HIGM1; GP39; T-BAM]

Other Names: [Tumor necrosis factor receptor superfamily member 5; Tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily member 5; CD40 antigen; B-cell surface antigen CD40; Bp50; CD40L receptor; CD_antigen: CD40]

Product Gene Name: [CD40]

Product Gene Name Synonyme: N/A

Other Gene Names: [Cd40; Cd40; IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5; AI326936; Tnfrsf5]

Clonality: Monoclonal

Isotype: IgG2a, kappa

Clone: [FGK45.5]

Host: Rat

Reactivity: Mouse
Does not react with Human.

Specificity: Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF)