MBS4381466 | Vitronectin Receptor/CD51/CD61

Vitronectin Receptor/CD51/CD61 | MBS4381466 | Mybiosource

Product Short Name: [Vitronectin Receptor/CD51/CD61]

Product Name Synonyme: [CD51; DKFZp686A08142; integrin alpha V beta 3; Integrin alpha-5 Integrin alpha-V light chain; integrin alphaVbeta3; integrin; alpha V (vitronectin receptor; alpha polypeptide; antigen CD51); ITGAV; Msk8; VNRA; VTNR]

Other Names: [integrin alpha-V isoform 2; Integrin alpha-V; integrin alpha-V; integrin subunit alpha V; Vitronectin receptor subunit alpha]

Product Gene Name: [ITGAV]

Product Gene Name Synonyme: N/A

Other Gene Names: [ITGAV; ITGAV; CD51; MSK8; VNRA; VTNR; MSK8; VNRA]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [23C6]

Host: Mouse

Reactivity: Human, Chicken
Does not react with Bovine or Pig or Rabbit.

Specificity: ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin Receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. Reacts with Integrin Alpha V Beta 3. 23C6 may be useful for bone resorption modulation, osteoclast identification, receptor purification, malignant melanoma identification and treatment.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: ELISA (EIA)