MBS4381363 | MRP3 (Multidrug Resistance-Associated Protein 3)

MRP3 (Multidrug Resistance-Associated Protein 3) | MBS4381363 | Mybiosource

Product Short Name: [MRP3 (Multidrug Resistance-Associated Protein 3)]

Product Name Synonyme: [ABC31; ATP-binding cassette sub-family C member 3 (ABCC3); Canalicular multispecific organic anion transporter 2 (CMOAT2); MLP2; MOATD; Multi-specific organic anion transporter D; Multidrug resistance-associated protein 3]

Other Names: [canalicular multispecific organic anion transporter 2 isoform 2; Canalicular multispecific organic anion transporter 2; canalicular multispecific organic anion transporter 2; ATP binding cassette subfamily C member 3; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3]

Product Gene Name: [MRP3]

Product Gene Name Synonyme: [ABCC3]

Other Gene Names: [ABCC3; ABCC3; MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757; CMOAT2; MLP2; MRP3; MOAT-D]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [ABCC3/2971]

Host: Mouse

Reactivity: Human

Specificity: The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood. The MRP gene family also includes MRP2, which is alternatively designated cMOAT (for canalicular multispecific organic anion transporter) and MRP3, which are both conjugate export pumps exp- ressed predominantly in hepatocytes. MRP2 localizes exclusively to the apical membrane and is constitutively expressed at a high level in normal liver cells. Conversely, MRP3 localizes to the basolateral membrane where it also medi- ates the transport of the organic anion S-(2,4-dinitrophenyl-) glutathione toward the basolateral side of the membrane. MRP3 is normally expressed at comparatively lower levels than MRP2 and increases only when secretion across the apical membrane by MRP2 is impaired.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistochemistry (IHC) Paraffin