MBS4381359 | Calpastatin

Calpastatin | MBS4381359 | Mybiosource

Product Short Name: [Calpastatin]

Product Name Synonyme: [BS 17; Calpain inhibitor; Calpastatin; Cast; Heart type calpastatin; Sperm BS 17 component]

Other Names: [Calpastatin; Calpastatin; calpastatin; calpastatin; Calpain inhibitor; Sperm BS-17 component]

Product Gene Name: [CAST]

Product Gene Name Synonyme: N/A

Other Gene Names: [CAST; CAST; BS-17; PLACK]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [CAST/1550]

Host: Mouse

Reactivity: Human

Specificity: Calpastatin is an intracellular calcium-dependent protease that cleaves cytoskeletal and sub-membranous proteins. Calpains are non-lysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2+- dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits, designated Calpastatin, Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpastatin co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: ELISA (EIA), Immunohistochemistry (IHC) Paraffin