MBS4381317 | Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker)

Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) | MBS4381317 | Mybiosource

Product Short Name: [Thyroid Stimulating Hormone, beta (TSH beta)]

Product Name Synonyme: [CHNG4; Thyroid stimulating hormone beta subunit; Thyroid stimulating hormone; beta precursor; Thyrotropin beta subunit; TSHB]

Other Names: [thyrotropin subunit beta isoform 1; Thyrotropin subunit beta; thyrotropin subunit beta; thyroid stimulating hormone subunit beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain; INN: Thyrotropin alfa]

Product Gene Name: [TSHB]

Product Gene Name Synonyme: N/A

Other Gene Names: [TSHB; TSHB; TSH-B; TSH-BETA; TSH-B; TSH-beta]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [TSHb/1317]

Host: Mouse

Reactivity: Human

Specificity: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistochemistry (IHC) Paraffin