MBS4381289 | TIMP1 (Marker of Lymph Node Metastasis)

TIMP1 (Marker of Lymph Node Metastasis) | MBS4381289 | Mybiosource

Product Short Name: [TIMP1]

Product Name Synonyme: [Collagenase inhibitor; EPO; Erythroid-Potentiating Activity (EPA); Fibroblast collagenase inhibitor; Human Collagenase Inhibitor (HCI); Metalloproteinase inhibitor 1; Tissue Inhibitor of Metalloproteinase 1 (TIMP1)]

Other Names: [metalloproteinase inhibitor 1; Metalloproteinase inhibitor 1; metalloproteinase inhibitor 1; TIMP metallopeptidase inhibitor 1; Erythroid-potentiating activity; EPA; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1]

Product Gene Name: [TIMP1]

Product Gene Name Synonyme: N/A

Other Gene Names: [TIMP1; TIMP1; EPA; EPO; HCI; CLGI; TIMP; TIMP-1; CLGI; TIMP; EPA; Collagenase inhibitor; TIMP-1]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [2A5]

Host: Mouse

Reactivity: Human

Specificity: TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity). PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: ELISA (EIA)