MBS4381278 | Tal1

Tal1 | MBS4381278 | Mybiosource

Product Short Name: [Tal1]

Product Name Synonyme: [bHLHa17; Class A basic helix-loop-helix protein 17; OTTHUMP00000009563; OTTHUMP00000009564; SCL; STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR; Stem cell protein; T cell acute lymphocytic leukemia 1; T cell acute lymphocytic leukemia 1 protein; T cell acute lymphocytic leukemia 1 protein; T cell leukemia/lymphoma 5 protein; T-cell acute lymphocytic leukemia protein 1; T-cell leukemia/lymphoma protein 5; Tal 1 product; TAL 1 protein; TAL bHLH transcription factor 1 erythroid differentiation factor; TAL-1]

Other Names: [T-cell acute lymphocytic leukemia protein 1 isoform 1; T-cell acute lymphocytic leukemia protein 1; T-cell acute lymphocytic leukemia protein 1; TAL bHLH transcription factor 1, erythroid differentiation factor; Class A basic helix-loop-helix protein 17; bHLHa17; Stem cell protein; T-cell leukemia/lymphoma protein 5]

Product Gene Name: [TAL1]

Product Gene Name Synonyme: N/A

Other Gene Names: [TAL1; TAL1; SCL; TCL5; tal-1; bHLHa17; BHLHA17; SCL; TCL5; TAL-1; bHLHa17]

Clonality: Monoclonal

Isotype: IgG2a, kappa

Clone: [TAL1/2707]

Host: Mouse

Reactivity: Human

Specificity: Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: ELISA (EIA)