MBS4381112 | Nucleolin (Marker of Human Cells)

Nucleolin (Marker of Human Cells) | MBS4381112 | Mybiosource

Product Short Name: [Nucleolin]

Product Name Synonyme: [NCL; Nucl; Nucleolin; Protein C23]

Other Names: [nucleolin; Nucleolin; nucleolin; nucleolin; Protein C23]

Product Gene Name: [NCL]

Product Gene Name Synonyme: N/A

Other Gene Names: [NCL; NCL; C23; Nsr1]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [NCL/902]

Host: Mouse

Reactivity: Human
Does not react with Mouse, Rat or Cow.

Specificity: Recognizes a protein of ~76kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly.This MAb can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.

Purity: Purified Ab conjugated to CF488

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 4 to 8 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF)