MBS4381067 | Lymphocyte Specific Protein 1 (LSP1)/pp52

Lymphocyte Specific Protein 1 (LSP1)/pp52 | MBS4381067 | Mybiosource

Product Short Name: [Lymphocyte Specific Protein 1 (LSP1)/pp52]

Product Name Synonyme: [WP34; pp52; lymphocyte specific protein 1; leukocyte specific protein 1]

Other Names: [lymphocyte-specific protein 1 isoform 2; Lymphocyte-specific protein 1; lymphocyte-specific protein 1; lymphocyte specific protein 1; 47 kDa actin-binding protein; 52 kDa phosphoprotein; pp52; Lymphocyte-specific antigen WP34]

Product Gene Name: [LSP1]

Product Gene Name Synonyme: N/A

Other Gene Names: [LSP1; LSP1; WP34; pp52; WP34; pp52]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [LSP1/3042]

Host: Mouse

Reactivity: Human

Specificity: LSP1 is a hematopoietic-expressed gene that encodes an F-actin-binding, leukocyte-specific (including B and T lymphocytes, granulocytes and macrophages), phosphoprotein. However, mRNA splice variants that do not encode the lympho-specific protein are expressed from this gene in nonlymphoid cell lines as well (myocytes, stromal cells and fibroblasts), suggesting pp52 has a divergent role in signal transduction. The pp52 (LSP1) locus maps to human chromosome 11p15.5, which is implicated in tumor-related chromosomal translocations found in chronic lymphocytic leukemia. The pp52 promoter contains key elements that control transcriptional activity including an initiator specifying the unique 5' terminus of pp52 mRNA, tandem pairs of Ets and SP1 motifs, and a single C/EBP motif. LSP1 binds the cytoskeleton and has been implicated in affecting cytoskeletal remodeling in a variety of leukocyte functions, including cell motility and chemotaxis.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: ELISA (EIA)