MBS4381019 | IL-4/Interleukin 4

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MBS4381019
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Description

IL-4/Interleukin 4 | MBS4381019 | Mybiosource

Product Short Name: [IL-4/Interleukin 4]

Product Name Synonyme: [B cell growth factor 1; B cell IgG differentiation factor; B Cell Stimulatory Factor 1; BCGF1; Binetrakin; BSF1; IGG1 induction factor; Il4e12; Interleukin 4 variant 2; Interleukin 4; isoform 1Lymphocyte stimulatory factor 1; MGC79402; Pitrakinra]

Other Names: [interleukin-4 isoform 1; Interleukin-4; interleukin-4; interleukin 4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra]

Product Gene Name: [IL-4]

Product Gene Name Synonyme: [HIL41]

Other Gene Names: [IL4; IL4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1; IL-4; BSF-1]

Clonality: Monoclonal

Isotype: IgG2b, kappa

Clone: [IL4/1597]

Host: Mouse

Reactivity: Human

Specificity: Interleukin-4 (IL-4), also designated B cell stimulatory factor-1, is a glycosylated cytokine secreted by activated T lymphocytes, basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2, TNF, while Th2 cells secrete IL-4, IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells, but suppress the production of IgM, IgA, IgG1, IgG2 and IgG3. It has been determined that Stat6 is rapidly tyrosine phosphorylated following stimulation of IL-3 or IL-4, but is not detectably phosphorylated following stimulation with IL-2, IL-12 or erythropoietin.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: ELISA (EIA)

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