MBS4380682 | S100A4 (Marker of Tumor Metastasis)

S100A4 (Marker of Tumor Metastasis) | MBS4380682 | Mybiosource

Product Short Name: [S100A4]

Product Name Synonyme: [S100 calcium-binding protein A4; Calvasculin; CAPL; Fibroblast specific protein 1 (FSP1); Leukemia multidrug resistance associated protein; Malignant transformation suppression 1 (MTS1); Metastasin; Placental calcium-binding protein]

Other Names: [protein S100-A4; Protein S100-A4; protein S100-A4; S100 calcium binding protein A4; Calvasculin; Metastasin; Placental calcium-binding protein; Protein Mts1; S100 calcium-binding protein A4]

Product Gene Name: [S100A4]

Product Gene Name Synonyme: N/A

Other Gene Names: [S100A4; S100A4; 42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98; CAPL; MTS1]

Clonality: Monoclonal

Isotype: IgG2c

Clone: [CPTC-S100A4-3]

Host: Mouse

Reactivity: Human. Others not tested.

Specificity: S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100A4 has been implicated in the progression and prognosis of several forms of human cancer, e.g. breast, colorectal, gastric, pancreatic and bladder cancer, SCLC and oesophageal squamous cell carcinoma, among others. Poor prognosis associated with high S100A4 expression is accompanied by clear signs of disease progression, e.g. high histological and clinical grades and involvement of lymph nodes. Also indicative of poor prognosis is high S100A4 expression coupled with reduced E-cadherin expression in pancreatic, oral squamous cell carcinoma and in melanoma. S100A4 expression is inversely related with expression of metastasis suppressor nm23 and with prognosis of breast cancer. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Western Blot (WB), Immunohistology (Formalin-Fixed)