MBS4380540 | Cathepsin D (Tumor Marker)

Cathepsin D (Tumor Marker) | MBS4380540 | Mybiosource

Product Short Name: [Cathepsin D]

Product Name Synonyme: [CatD; Cathepsin D; Ceroid lipofuscinosis neuronal 10; CLN10; CPSD; Epididymis secretory sperm binding protein Li 130P; Lysosomal aspartyl peptidase; Lysosomal aspartyl protease]

Other Names: [cathepsin D preproprotein; Cathepsin D; cathepsin D; cathepsin D]

Product Gene Name: [CTSD]

Product Gene Name Synonyme: N/A

Other Gene Names: [CTSD; CTSD; CPSD; CLN10; HEL-S-130P; CPSD]

Clonality: Monoclonal

Isotype: IgG1

Clone: [CTSD/2781]

Host: Mouse

Reactivity: Human. Others not known

Specificity: Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43kDa preprocathepsin D that is cleaved and glycosylated to form a 46kDa procathepsin D and then further cleaved to produce 28kDa and 15kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistology (Formalin-Fixed)