MBS4380454 | CD11c (Dendritic Cell Marker)

CD11c (Dendritic Cell Marker) | MBS4380454 | Mybiosource

Product Short Name: [CD11c]

Product Name Synonyme: [CD11 antigen-like family member C; Complement component 3 receptor 4 subunit; Integrin alpha-X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); Leu M5 alpha subunit; Leukocyte adhesion glycoprotein p150 95 alpha chain; Myeloid membrane antigen alpha subunit; p150/95]

Other Names: [integrin alpha-X isoform 2; Integrin alpha-X; integrin alpha-X; integrin subunit alpha X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD_antigen: CD11c]

Product Gene Name: [CD11c]

Product Gene Name Synonyme: [ITGAX]

Other Gene Names: [ITGAX; ITGAX; CD11C; SLEB6; CD11C]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [ITGAX/2507]

Host: Mouse

Reactivity: Human. Others not known.

Specificity: Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: N/A

Tested Application: Immunohistochemistry (IHC) Formalin