MBS4380301 | Cyclin E (G1/S-Phase Cyclin)

Cyclin E (G1/S-Phase Cyclin) | MBS4380301 | Mybiosource

Product Short Name: [Cyclin E]

Product Name Synonyme: [CCNE1; Cyclin E1; G1/S-specific cyclin-E1]

Other Names: [T-cell surface glycoprotein CD5 isoform 2; T-cell surface glycoprotein CD5; T-cell surface glycoprotein CD5; CD5 molecule; Lymphocyte antigen T1/Leu-1; CD_antigen: CD5]

Product Gene Name: [CCNE1]

Product Gene Name Synonyme: N/A

Other Gene Names: [CD5; CD5; T1; LEU1; LEU1]

Clonality: Monoclonal

Isotype: IgG2b, kappa

Clone: [CCNE1/2460]

Host: Mouse

Reactivity: Human. Others not known.

Specificity: Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistochemistry (IHC) Formalin