MBS4380233 | CD43 (T-Cell Marker)

CD43 (T-Cell Marker) | MBS4380233 | Mybiosource

Product Short Name: [CD43]

Product Name Synonyme: [Galactoglycoprotein; GALGP; GPL115; Leukocyte sialoglycoprotein; Leukosialin; LSN; Sialophorin; SPN]

Other Names: [leukosialin; Leukosialin; leukosialin; sialophorin; GPL115]

Product Gene Name: [CD43]

Product Gene Name Synonyme: [SPN]

Other Gene Names: [SPN; SPN; LSN; CD43; GALGP; GPL115; CD43; CD43ct]

Clonality: Monoclonal

Isotype: IgG

Clone: [SPN/2049R]

Host: Rabbit

Reactivity: Human. Others not known.

Specificity: It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. From 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors of lymphoma.

Purity: N/A

Form: 200ug/ml of Ab purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Immunohistochemistry (IHC) Formalin