MBS4380214 | CD269/TNFRSF17/BCMA (B-Cell Maturation Protein)

CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) | MBS4380214 | Mybiosource

Product Short Name: [CD269/TNFRSF17/BCMA (B-Cell Maturation Protein)]

Product Name Synonyme: [B-cell maturation protein; BCMA; CD269; TNR17; Tumor necrosis factor receptor superfamily member 17 (TNFRSF17)]

Other Names: [tumor necrosis factor receptor superfamily member 17; Tumor necrosis factor receptor superfamily member 17; tumor necrosis factor receptor superfamily member 17; TNF receptor superfamily member 17; B-cell maturation protein; CD_antigen: CD269]

Product Gene Name: [CD269]

Product Gene Name Synonyme: [TNFRSF17; BCMA]

Other Gene Names: [TNFRSF17; TNFRSF17; BCM; BCMA; CD269; TNFRSF13A; BCM; BCMA]

Clonality: Monoclonal

Isotype: IgG2b, kappa

Clone: [BCMA/2366]

Host: Mouse

Reactivity: Human. Others not known.

Specificity: The B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: ELISA (EIA), Immunohistochemistry (IHC) Formalin