MBS4380054 | CD61/Integrin beta-3/Platelet Glycoprotein IIIa (Platelet Marker)

CD61/Integrin beta-3/Platelet Glycoprotein IIIa (Platelet Marker) | MBS4380054 | Mybiosource

Product Short Name: [CD61/Integrin beta-3/Platelet Glycoprotein IIIa]

Product Name Synonyme: [BDPLT2; GP3A; GPIIIa; GT; HPA 1; HPA 4; Integrin beta-3; ITGB3; NAIT; Platelet fibrinogen receptor beta subunit; Platelet glycoprotein IIIa; PTP]

Other Names: [integrin beta-3; Integrin beta-3; integrin beta-3; integrin subunit beta 3; Platelet membrane glycoprotein IIIa; GPIIIa; CD_antigen: CD61]

Product Gene Name: [CD61]

Product Gene Name Synonyme: [ITGB3]

Other Gene Names: [ITGB3; ITGB3; GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; GP3A; GPIIIa]

Clonality: Monoclonal

Isotype: IgG1, kappa

Clone: [ITGB3/1713]

Host: Mouse

Reactivity: Human. Others not tested.

Specificity: Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the alphaV-chain (CD51) to form vitronectin receptor, or with the alphaIIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61). The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin