MBS4380016 | CD209/DC-SIGN (Pathogen Receptor on Dendritic Cells)

CD209/DC-SIGN (Pathogen Receptor on Dendritic Cells) | MBS4380016 | Mybiosource

Product Short Name: [CD209/DC-SIGN]

Product Name Synonyme: [CD209; CDSIGN; CIRE; CLEC4L; DC-SIGN; DC-SIGN1; DCSIGN; Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1; HIV GP120 Binding Protein; SIGN-R1; SIGNR5]

Other Names: [CD209 antigen isoform 5; CD209 antigen; CD209 antigen; CD209 molecule; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1; CD_antigen: CD209]

Product Gene Name: [CD209]

Product Gene Name Synonyme: [DC-SIGN]

Other Gene Names: [CD209; CD209; CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; CLEC4L; DC-SIGN; DC-SIGN1]

Clonality: Monoclonal

Isotype: IgG2b, kappa

Clone: [C209/1781]

Host: Mouse

Reactivity: Human. Others not known.

Specificity: DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

Purity: N/A

Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: N/A

Storage Stability: Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin