MBS246262 | Mouse Monoclonal [clone AE3] (IgG1) to Human Cytokeratin Type II

Mouse Monoclonal [clone AE3] (IgG1) to Human Cytokeratin Type II | MBS246262 | MyBiosource

Product Short Name: [Cytokeratin Type II]

Product Name Synonyme: [Anti-Cytokeratin Type II Antibody (clone AE3) IHC-plus; Cytokeratin Type II; Human Cytokeratin Type II]

Other Names: [cytokeratin type II; Keratin, type II cytoskeletal 75; Cytokeratin-75; CK-75; Keratin-6 hair follicle; hK6hf; Keratin-75; K75; Type II keratin-K6hf; Type-II keratin Kb18]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [KRT75; K6HF; KB18; CK-75; hK6hf; K75]

Clonality: Monoclonal

Isotype: IgG1

Clone: [AE3]

Host: Mouse

Reactivity: Human

Specificity: This antibody has shown to recognize most of the basic (type II) keratins. Each epithelium contains at least one basic keratin. In this way AE-3 is broadly reactive with almost all epithelial and there neoplasms. This antibody together with AE-1 has been used for studying the immuno-localization of epidermal keratins, tissue distribution and epithelia development. AE-1 and AE-3 have also been used extensively, individually or mixed, for distinguishing carcinoma from non-carcinoma. The antibody is cross-reactive with keratins of rabbit, mouse, rat, bovine and chicken. Within immunoblots AE-1 detects distinct MW's of 52 kD, 54 kD, 56 kD, 58 kD, 59 kD, 64 kD, and 65-67 kD with all Ip's lower then 6.0. These MW's are believed to correspond with respectively keratin 8, 7, 6, 5, 4, 3 and 1 & 2.

Purity: Purified IgG

Form: 0.01M PBS containing 0.1% Sodium azide and 1% BSA. Sourced in Ascites.

Concentration: 1 mg/ml

Storage Stability: Store at 4 degree C.

Tested Application: Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Western Blot (WB)