MBS224263 | GOAT ANTI Bcl-2 (N-TERMINAL)

GOAT ANTI Bcl-2 (N-TERMINAL) | MBS224263 | MyBiosource

Product Short Name: [Bcl-2 ]

Product Name Synonyme: N/A

Other Names: [apoptosis regulator Bcl-2 alpha isoform; Apoptosis regulator Bcl-2; apoptosis regulator Bcl-2; protein phosphatase 1, regulatory subunit 50; B-cell CLL/lymphoma 2]

Product Gene Name: [Bcl-2]

Product Gene Name Synonyme: N/A

Other Gene Names: [BCL2; BCL2; Bcl-2; PPP1R50]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Goat

Reactivity: Mouse (Expected from Sequence), Rat (Expected from Sequence)

Specificity: This item detects an epitope within the N-terminal (NT) region of Bcl-2, a 25kD integral outer mitochondrial membrane protein that blocks apoptotic death in a variety of cell systems. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability. It inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (apaf-1). Bcl-2 is antiproliferative by facilitating G0 entry.

Constitutive expression of Bcl-2 is thought to be the cause of follicular lymphoma, also known as type II chronic lymphatic leukaemia. Bcl-2 mutations have also been found in Non-Hodgkin Lymphomas.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 0.5mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Western Blot (WB)