MBS224236 | RABBIT ANTI HUMAN CD294 (N-TERMINAL)

RABBIT ANTI HUMAN CD294 (N-TERMINAL) | MBS224236 | MyBiosource

Product Short Name: [CD294]

Product Name Synonyme: N/A

Other Names: [prostaglandin D2 receptor 2; Prostaglandin D2 receptor 2; prostaglandin D2 receptor 2; G protein-coupled receptor 44; G-protein coupled receptor 44; PGD2 receptor; chemoattractant receptor-homologous molecule expressed on TH2 cells; prostaglandin D2 receptor CRTH2; prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CD_antigen: CD294, Gpr44]

Product Gene Name: [CD294]

Product Gene Name Synonyme: N/A

Other Gene Names: [Ptgdr2; Ptgdr2; Crth2; Gpr44; Grp45; Crth2]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: Mouse (Expected from Sequence), Rat (Expected from Sequence)

Specificity: This item recognises CD294, also known as chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) and GRP44.

CD294 is a G protein-coupled receptor which has a high affinity for prostaglandin D2 (PGD2).

CD294 is predominantly expressed on Th2 cells, basophils and eosinophils, and its activation by PDG2 mediates chemotaxis of these cells to inflammatory sites. CD294 may be a useful marker for Th2 cells, and enhances their function and signalling with a possible role in Th2 cell differentiation.

PGD2 is thought to contribute to bronchoconstriction, eosinophilia and mucus production in allergic asthma, and CD294 may contribute to this disease.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 1.0mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of despatch.

Tested Application: ELISA (EIA), Immunohistology Paraffin, Western Blot (WB)