MBS223337 | RABBIT ANTI HUMAN FTO

RABBIT ANTI HUMAN FTO | MBS223337 | MyBiosource

Product Short Name: [FTO]

Product Name Synonyme: N/A

Other Names: [alpha-ketoglutarate-dependent dioxygenase FTO; Alpha-ketoglutarate-dependent dioxygenase FTO; alpha-ketoglutarate-dependent dioxygenase FTO; AlkB homolog 9; fat mass and obesity-associated protein; protein fto; fat mass and obesity associated; Fat mass and obesity-associated protein]

Product Gene Name: [FTO]

Product Gene Name Synonyme: N/A

Other Gene Names: [FTO; FTO; ALKBH9; KIAA1752]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: N/A

Specificity: This item recognises human FTO, otherwise known as fat mass and obesity-associated protein, a 60kDa protein expressed ubiquitously with particularly high levels in the adrenal glands and brain. The gene was named FTO because a deletion in it resulted in fused toes and other abnormalities in mice. Since then, some correlation has been shown between carriers of the gene and obesity as well as an increased risk of Type 2 diabetes.

The precise function of the gene is unknown but it shows homology with the enzyme AlkB, which oxidatively demethylates DNA. FTO gene expression has been shown to be highly upregulated in rats after food deprivation. A negative correlation with the expression of orexin peptide, which is involved in the stimulation of food intake, has also been found.

Purity: N/A

Form: Serum
Serum - liquid

Concentration: N/A

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Western Blot (WB)