MBS223258 | RABBIT ANTI AID (C-TERMINAL)

RABBIT ANTI AID (C-TERMINAL) | MBS223258 | MyBiosource

Product Short Name: [AID ]

Product Name Synonyme: N/A

Other Names: [single-stranded DNA cytosine deaminase; Single-stranded DNA cytosine deaminase; single-stranded DNA cytosine deaminase; cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; activation-induced cytidine deaminase; Activation-induced cytidine deaminase; Cytidine aminohydrolase]

Product Gene Name: [AID]

Product Gene Name Synonyme: N/A

Other Gene Names: [AICDA; AICDA; AID; ARP2; CDA2; HIGM2; HEL-S-284; AID]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: N/A

Specificity: This item recognises an epitope within the C-terminal region (CT) of Activation-induced cytidine deaminase (AID), a 24kDa homologue of the RNA-editing cytidine deaminase enzyme, APOBEC-1.

Although the molecular mechanisms by which AID acts remain unclear, a growing number of studies reveal a requirement for AID during somatic hypermutation (SHM) and class switch recombination (CSR). These genetic modification events take place within highly specialised B cell germinal centres, during the final maturation stages of B cells, giving rise to high-affinity antibodies which use CSR to switch from IgM to IgG, IgA or IgE isotypes.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 1.0mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Western Blot (WB)