MBS222935 | RABBIT ANTI BRCC36

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SKU:
MBS222935
Availability:
Usually Shipped in 5 Working Days
Size:
0.1 mg
NULL579.00
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Description

RABBIT ANTI BRCC36 | MBS222935 | MyBiosource

Product Short Name: [BRCC36]

Product Name Synonyme: N/A

Other Names: [lys-63-specific deubiquitinase BRCC36 isoform 2; Lys-63-specific deubiquitinase BRCC36; lys-63-specific deubiquitinase BRCC36; BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 36; BRISC complex subunit BRCC36; BRCA1/BRCA2-containing complex, subunit 3; BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 3; BRCA1/BRCA2-containing complex subunit 36; BRISC complex subunit BRCC36]

Product Gene Name: [BRCC36]

Product Gene Name Synonyme: N/A

Other Gene Names: [BRCC3; BRCC3; C6.1A; BRCC36; CXorf53; BRCC36; C6.1A; CXorf53]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: Mouse, Rat

Specificity: This item recognises human BRCA1/BRCA2 complex subunit 36 (BRCC36), a 36.7kDa nuclear protein.

BRCC36, together with BRCA1, BRCA2, Rad51 and BRCC45, forms a holoenzyme complex that possesses an ubiquitin E3 ligase activity.

Studies have demonstrated that BRCC36 functions in enhancing cellular survival following DNA damage and that it is essential for ionizing radiation induced BRCA1 phosphorylation and nuclear foci formation.

Research has shown that BRCC36 is aberrantly expressed in the majority of breast tumours indicating a potential role in the pathogenesis of the disease. It has been hypothesized that BRCC36 could be a potentially important target in the treatment of radiation-resistant breast tumours.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 1.0mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunohistology Paraffin*, Western Blot (WB)

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