MBS222908 | RABBIT ANTI GLI3

RABBIT ANTI GLI3 | MBS222908 | MyBiosource

Product Short Name: [GLI3]

Product Name Synonyme: N/A

Other Names: [transcriptional activator GLI3; Transcriptional activator GLI3; transcriptional activator GLI3; GLI-Kruppel family member GLI3; glioma-associated oncogene family zinc finger 3; oncogene GLI3; zinc finger protein GLI3; GLI family zinc finger 3; GLI3 form of 190 kDa; GLI3-190; GLI3 full length protein; GLI3FL]

Product Gene Name: [GLI3]

Product Gene Name Synonyme: N/A

Other Gene Names: [GLI3; GLI3; PHS; ACLS; GCPS; PAPA; PAPB; PAP-A; PAPA1; PPDIV; GLI3FL; GLI3-190; GLI3-190; GLI3FL; GLI3-83]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: Amphibia, Chicken, Chimpanzee, Dog, Monkey, Mouse, Quail, Rat

Specificity: This item recognizes the Human Zinc Finger protein 3 (GLI-3), also known as GLI-Kruppel family member 3, a 169.8kDa protein belonging to the GLI C2H2-type zinc finger protein of transcription factors.

GLI-3 and the related GLI-2 proteins are the primary transcription factors that mediate Sonic hedgehog (Shh) signals in the mouse, GLI-2 being primarily a transcriptional activator while GLI-3 is a transcriptional repressor. GLI-3 plays a role in the development of the limbs and brain. It is expressed in a wide range of adult tissues including the colon, lung, spleen, testis and placenta.

Defects in GLI3 are causative of a range of disease states including Pallister-Hall syndrome, type IV preaxial polydactyly, acrocallosal syndrome (ACS) and Greig cephalo-poly-syndactyly syndrome.
GLI proteins are also implicated as potent oncogenes in the embryonal carcinoma cell.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 0.5mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)