MBS222895 | RABBIT ANTI HUMAN PTK7 (N-TERMINAL)

RABBIT ANTI HUMAN PTK7 (N-TERMINAL) | MBS222895 | MyBiosource

Product Short Name: [PTK7 ]

Product Name Synonyme: N/A

Other Names: [inactive tyrosine-protein kinase 7 isoform e; Inactive tyrosine-protein kinase 7; inactive tyrosine-protein kinase 7; PTK7 protein tyrosine kinase 7; colon carcinoma kinase 4; pseudo tyrosine kinase receptor 7; tyrosine-protein kinase-like 7; protein tyrosine kinase 7 (inactive); Colon carcinoma kinase 4; CCK-4; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Tyrosine-protein kinase-like 7]

Product Gene Name: [PTK7]

Product Gene Name Synonyme: N/A

Other Gene Names: [PTK7; PTK7; CCK4; CCK-4; CCK4; CCK-4]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: Mouse, Rat

Specificity: This item recognises human Protein tyrosine kinase-like 7 (PTK7), a member of the receptor tyrosine kinase family, otherwise known as Colon Carcinoma Kinase 4 (CCK4). PTK7 is highly expressed in the kidney, liver, lung, pancreas and melanocytes with weaker expression being detected in the thyroid gland, ovaries, brain, heart and skeletal muscle.

PTK7 may play a role in embryonic development. It is thought to function as a cell adhesion molecule and as a novel regulator of the planar cell polarity (PCP) pathway in vertebrates.

Studies also suggest that PTK7 may be involved in the tumour progression. A loss of PTK7 expression has been observed in melanoma cell lines, whereas increased levels of PTK7 have been detected in high-throughput acute myeloid leukaemia samples. In addition, PTK7 is not expressed in normal colon but has been detected in colon carcinomas and as such is a potential marker for tumour progression.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 1.0 mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunohistology Paraffin*, Western Blot (WB)