MBS222350 | RABBIT ANTI Cdk5 (C-TERMINAL)

RABBIT ANTI Cdk5 (C-TERMINAL) | MBS222350 | MyBiosource

Product Short Name: [Cdk5 ]

Product Name Synonyme: N/A

Other Names: [cyclin-dependent-like kinase 5 isoform 2; Cyclin-dependent-like kinase 5; cyclin-dependent-like kinase 5; TPKII catalytic subunit; cell division protein kinase 5; protein kinase CDK5 splicing; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; cyclin-dependent kinase 5; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit]

Product Gene Name: [Cdk5]

Product Gene Name Synonyme: N/A

Other Gene Names: [CDK5; CDK5; PSSALRE; CDKN5; TPKII catalytic subunit]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: Mouse, Rat

Specificity: This item detects human cyclin dependent kinase 5 (Cdk5), a proline-directed serine/threonine protein kinase that unlike most Cdks does not function in cell cycle control, and is not regulated by cyclins. Instead, it requires the association p35 or p39 for its kinase activity, resulting in a master regulator of neuronal functions, with roles in neuronal survival and migration, neurotransmitter release and axon guidance.

Cdk5 is ubiquitously expressed, but expression and activity is highest in post mitotic neurones, where p35 and p39 are highly expressed. Deregulation of this kinase is neurotoxic and might contribute to the pathogenesis of Alzheimer's disease and other neurodegenerative disorders.

Purity: N/A

Form: Serum
Serum - liquid

Concentration: N/A

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)