MBS222345 | GOAT ANTI CHOLESTEROL 24-HYDROXYLASE (C-TERMINAL)

GOAT ANTI CHOLESTEROL 24-HYDROXYLASE (C-TERMINAL) | MBS222345 | MyBiosource

Product Short Name: [CHOLESTEROL 24-HYDROXYLASE ]

Product Name Synonyme: N/A

Other Names: [cholesterol 24-hydroxylase; Cholesterol 24-hydroxylase; cholesterol 24-hydroxylase; CH24H; cytochrome P450 46A1; cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase); cytochrome P450, family 46, subfamily A, polypeptide 1; Cytochrome P450 46A1]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [CYP46A1; CYP46A1; CP46; CYP46; CYP46; CH24H]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Goat

Reactivity: N/A

Specificity: This item recognises cholesterol 24-hydroxylase (CYP46A1), a 58 kDa member of the Cytochrome P450 family, expressed in the brain. CYP46A1 converts cholesterol into the biologically active oxysterol and 24(S)-hydroxycholesterol, in the first step of the enzymatic degradation of cholesterol in the brain. CYP46A1 is also thought to play a role in the metabolism of neurosteroids and drugs that can cross the blood-brain barrier and are targeted to the central nervous system.

P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members: CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1.

Purity: N/A

Form: Serum
Serum - liquid

Concentration: N/A

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Western Blot (WB)