MBS222344 | GOAT ANTI AMYLOID PRECURSOR PROTEIN (aa44-63)

GOAT ANTI AMYLOID PRECURSOR PROTEIN (aa44-63) | MBS222344 | MyBiosource

Product Short Name: [AMYLOID PRECURSOR PROTEIN]

Product Name Synonyme: N/A

Other Names: [amyloid beta A4 protein isoform a; Amyloid beta A4 protein; amyloid beta A4 protein; alzheimer disease amyloid protein; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); cerebral vascular amyloid peptide; peptidase nexin-II; preA4; protease nexin-II; amyloid beta (A4) precursor protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [APP; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Goat

Reactivity: N/A

Specificity: This item recognises amyloid precursor protein (APP), a 130 kDa member of the APP family, expressed in adult brain. It is a cell surface kinesin I membrane receptor which regulates the axonal transport of beta-secretase and presenilin 1.In Alzheimer's disease processing of APP by beta-secretase gives rise to amyloidogenic 42 AA beta amyloid protein that is found in senile plaques and vessels. APP binds components of the extracellular matrix such as heparin and collagen I and IV, regulating neurite growth and is also involved in neuronal adhesion, cell mobility and axonogenesis. Through it's binding to APBB1/Tip60, APP plays a role in the regulation of transcription. APP also inhibits Notch signaling through it's interaction with NUMB.

Purity: N/A

Form: Serum
Serum - liquid

Concentration: N/A

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunohistology Frozen, ELISA (EIA), Immunohistology Paraffin, Western Blot (WB)