MBS222329 | RABBIT ANTI 14-3-3 BETA

RABBIT ANTI 14-3-3 BETA | MBS222329 | MyBiosource

Product Short Name: [14-3-3 BETA]

Product Name Synonyme: N/A

Other Names: [14-3-3 protein beta/alpha; 14-3-3 protein beta/alpha; Protein kinase C inhibitor protein 1; KCIP-1]

Product Gene Name: [14-3-3 BETA]

Product Gene Name Synonyme: N/A

Other Gene Names: [YWHAB; KCIP-1]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: Bovine, Human, Mouse, Rabbit, Rat

Specificity: This item recognises the acetylated N-terminal of 14-3-3 beta. It is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for it's different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein.

14-3-3 beta plays a role in the pathogenesis of systemic lupus erythematosus and is involved in negative regulation of p90 ribosomal S6 kinase activity and tuberous sclerosis tumour suppressor proteins. It also binds IGF-1 receptor, RAF1 and CDC25 phosphatases.

This item may not react with recombinant proteins that are not N-acetylated.

Purity: N/A

Form: Serum
Serum - liquid

Concentration: N/A

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from the date of despatch.

Tested Application: ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)