MBS221418 | RABBIT ANTI HUMAN CD167 (C-TERMINAL)

RABBIT ANTI HUMAN CD167 (C-TERMINAL) | MBS221418 | MyBiosource

Product Short Name: [CD167 ]

Product Name Synonyme: N/A

Other Names: [epithelial discoidin domain-containing receptor 1 isoform 4; Epithelial discoidin domain-containing receptor 1; epithelial discoidin domain-containing receptor 1; CD167 antigen-like family member A; PTK3A protein tyrosine kinase 3A; cell adhesion kinase; mammary carcinoma kinase 10; neuroepithelial tyrosine kinase; neurotrophic tyrosine kinase, receptor, type 4; protein-tyrosine kinase RTK-6; tyrosine kinase DDR; tyrosine-protein kinase CAK; discoidin domain receptor tyrosine kinase 1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; Mammary carcinoma kinase 10; MCK-10; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; TRK E; Tyrosine kinase DDR; Tyrosine-protein kinase CAK; CD_antigen: CD167a]

Product Gene Name: [CD167]

Product Gene Name Synonyme: N/A

Other Gene Names: [DDR1; DDR1; CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; CD167; EDDR1; MCK10; NTRK4; PTK3A; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE; Epithelial discoidin domain receptor 1; MCK-10]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: N/A

Specificity: This item detects an epitope within the C-terminal of human CD167, a Discoidin Domain Receptor (DDR) also known as DDR1. CD167, a receptor for collagen, is widely expressed in normal and transformed epithelial cells, and may regulate cell adhesion, proliferation and extracellular matrix remodelling.

CD167 is a 125kD protein which is partially processed into a 62kD membrane-anchored beta-subunit and a 54kD soluble alpha-subunit. This process, also termed shedding, is significantly enhanced upon CD167 activation.

CD167 has been demonstrated to be a direct transcriptional target of the p53 tumour suppressor gene, and is significantly over-expressed in breast, ovarian, oesophageal, and paediatric brain tumours.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 1.0mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunohistology Paraffin*