MBS221402 | RABBIT ANTI HUMAN PACE4

RABBIT ANTI HUMAN PACE4 | MBS221402 | MyBiosource

Product Short Name: [PACE4]

Product Name Synonyme: N/A

Other Names: [proprotein convertase subtilisin/kexin type 6 isoform i preproprotein; Proprotein convertase subtilisin/kexin type 6; proprotein convertase subtilisin/kexin type 6; paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; subtilisin-like proprotein convertase 4; subtilisin/kexin-like protease PACE4; proprotein convertase subtilisin/kexin type 6; Paired basic amino acid cleaving enzyme 4; Subtilisin-like proprotein convertase 4; SPC4; Subtilisin/kexin-like protease PACE4]

Product Gene Name: [PACE4]

Product Gene Name Synonyme: N/A

Other Gene Names: [PCSK6; PCSK6; SPC4; PACE4; PACE4; SPC4]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Rabbit

Reactivity: N/A

Specificity: This item detects an epitope within the internal region of human Paired basic amino acid cleaving system 4 (PACE4). PACE4 belongs to the subtilisin-like proprotein convertase family, and is a 100kD calcium dependent serine endoprotease located in the endoplasmic reticulum. It cleaves its substrates at their paired basic amino acid processing sites, converting them into their biologically active products. Several PACE4 substrates have been identified, including transforming growth factor beta-related proteins, proalbumin and von Willebrand factor.

In mouse, PACE4 has been shown to increase tumor cell invasiveness, and thus enhance tumor progression. It is thought to have a similar role in humans.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 1.0mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunohistology Paraffin