MBS221391 | GOAT ANTI IRAK4 (N-TERMINAL)

GOAT ANTI IRAK4 (N-TERMINAL) | MBS221391 | MyBiosource

Product Short Name: [IRAK4 ]

Product Name Synonyme: N/A

Other Names: [interleukin-1 receptor-associated kinase 4 isoform a; Interleukin-1 receptor-associated kinase 4; interleukin-1 receptor-associated kinase 4; renal carcinoma antigen NY-REN-64; interleukin-1 receptor-associated kinase 4; Renal carcinoma antigen NY-REN-64]

Product Gene Name: [IRAK4]

Product Gene Name Synonyme: N/A

Other Gene Names: [IRAK4; IRAK4; IPD1; REN64; IRAK-4; NY-REN-64; IRAK-4]

Clonality: Polyclonal

Isotype: IgG

Clone: N/A

Host: Goat

Reactivity: Chimpanzee (Expected from Sequence), Mouse (Expected from Sequence)

Specificity: This item detects an epitope within the N-terminal (NT) region of integrin-1 receptor-associated kinase 4 (IRAK4). IRAK4 has a molecular weight of 50kD, and is an important mediator in the signal transduction of Toll-like receptor (TLR) and interleukin-1 (IL-1) receptor family members. IRAK4 functions in this signal transduction pathway by binding to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signalling cascades leading to transcriptional up-regulation and mRNA stabilization.

IRAK4 is a key activator of TLR-mediated signal transductions and has crucial roles in innate immune responses. It is expressed by the liver, kidneys and skeletal muscle.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: IgG concentration 0.5 mg/ml

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: ELISA (EIA), Western Blot (WB)